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**Formoterol + levalbuterol** denotes co-administration of two inhaled selective beta-2 adrenergic receptor agonist bronchodilators rather than a recognized single fixed-dose drug product. Formoterol is a long-acting beta-2 agonist used for maintenance bronchodilation, while levalbuterol is the active R-enantiomer of albuterol and a short-acting beta-2 agonist used for rapid relief or prevention of bronchospasm. Both relax airway smooth muscle through beta-2 receptor activation; concurrent use can produce additive sympathomimetic effects, including tachycardia, blood-pressure elevation, tremor, and arrhythmia risk. Levalbuterol inhalation products are indicated for bronchospasm associated with reversible obstructive airway disease. ([dailymed.nlm.nih.gov](https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=f3ce78d9-e923-400e-b3cd-3e6124ac7f6d))
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