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Fortibone + calcium lactate + calcitriol + vitamin D3

Development stage
Unknown
Lead developer
GELITA
Modality
Peptides, Small Molecules
Administration
Oral, Subcutaneous, Parenteral
01

Overview

Fortibone-Frontier Medical and Dental College, Abbotabad refers to a specific therapeutic regimen evaluated in a pilot randomized controlled trial for the management of bone mineral density in postmenopausal women. The intervention consists of **Fortibone**, a bioactive collagen peptide (BCP) product manufactured by GELITA AG, administered in combination with a calcium and vitamin D3 supplement (marketed as Colabone by Vivapharm SA). Fortibone is composed of specific type I collagen peptides with a mean molecular weight of approximately 5 kDa, which function as biological signals to stimulate osteoblasts for increased collagen synthesis while simultaneously inhibiting osteoclast activity to reduce bone resorption. The regimen includes a daily 5g sachet of Fortibone along with an electrolyte mix containing 500 mg of calcium (as calcium lactate), 4 mcg of calcitriol, and 400 IU of vitamin D3. This combination therapy is designed to address both the protein matrix and mineral components of bone tissue to treat osteopenia and prevent the progression to osteoporosis.

Brand names
FortiboneColabone
Other names
Bioactive Collagen Peptides + Calcium + Vitamin D3
02

Targets

VDR (Vitamin D receptor)

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