Drug intelligence / Profile preview

fruquintinib + camrelizumab + capecitabine

Development stage
Unknown
Lead developer
Hutchison Medipharma
Modality
Monoclonal Antibodies → Antibody-Based Therapeutics, Small Molecules
Administration
Oral, Intravenous
01

Overview

This is a combination therapy consisting of three agents: fruquintinib (a selective VEGFR inhibitor), camrelizumab (a PD-1 inhibitor), and capecitabine (a fluoropyrimidine chemotherapy agent). While the exact combination of all three agents is not well-documented in the provided information, similar combinations have been studied. Fruquintinib is an oral multi-kinase inhibitor that selectively targets VEGFR1, VEGFR2, and VEGFR3, inhibiting angiogenesis. Camrelizumab is a PD-1 inhibitor that works by enhancing T-cell immune responses. Capecitabine is a prodrug that converts to 5-fluorouracil in tumor tissues. The combination likely aims to leverage synergistic effects between anti-angiogenic therapy, immunotherapy, and chemotherapy.

02

Targets

TS (Thymidylate synthase)PDCD1 (Programmed cell death protein 1 receptor)ULBP2 (UL16-binding protein 2)VEGFR3 (Vascular endothelial growth factor receptor 3)VEGFR-1 (Vascular endothelial growth factor receptor 1)VEGFR2 (Vascular endothelial growth factor receptor 2)

Beyond the preview

Go deeper on fruquintinib + camrelizumab + capecitabine.

Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.

Clinical trials

Full profile access

Follow clinical development from study design and recruitment through results.

  • Trial phase
  • Status
  • Readouts

Indications & development

Full profile access

Explore development by indication, patient population, and geography.

  • Indications
  • Development status
  • Countries

Licensing & deals

Full profile access

Trace asset ownership, licensing agreements, and commercial partnerships.

  • Partners
  • Deal terms
  • Milestones

Patents & exclusivity

Full profile access

Explore the patent landscape and regulatory exclusivity around an asset.

  • Patents
  • Expiration dates
  • Exclusivity

Competitive landscape

Full profile access

Compare development programs by target, modality, and indication.

  • Competing assets
  • Targets
  • Development stage

Research & analysis

Full profile access

Connect source evidence and development news to your research questions.

  • Publications
  • News
  • Analysis

Bring the full picture into focus.

See how Gosset can support your research on fruquintinib + camrelizumab + capecitabine.

Explore the full profile

Gosset Free

Get started with Gosset.

Enter your work email and we’ll be in touch with next steps.

Work email preferred.

Book a call