Drug intelligence / Profile preview

gabapentin + ropivacaine

Development stage
Unknown
Lead developer
Pfizer
Modality
Small Molecules
Administration
Oral, Local Injection, Infusion
01

Overview

A combination therapy consisting of gabapentin, an anticonvulsant medication, and ropivacaine, a local anesthetic. This combination is used primarily for pain management, particularly for neuropathic pain conditions such as trigeminal neuralgia and post-surgical pain. The combination provides superior pain control compared to either agent alone, with reduced gabapentin dosage requirements and fewer side effects.

02

Targets

CACNA2D2 (α2δ-2)CACNA2D1 (Voltage-gated calcium channel subunit alpha2/delta-1)NaV (Voltage-gated sodium channels)

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