Drug intelligence / Profile preview

GAIA-121-125 (B+)

Development stage: Preclinical
Lead developer: GAIA BioMedicine
Modality: CAR-NK Cells → Other Engineered Cells → Adoptive Cell Transfer → Cell Therapies, Lymphokine-Activated Killer Cells → Native Immune Cells → Adoptive Cell Transfer → Cell Therapies
Administration: Intravenous

Overview

GAIA-121-125 (B+) is a preclinical-stage allogeneic cell therapy candidate developed by GAIA BioMedicine. It utilizes the company's proprietary GAIA Antibody-Armed Approach (GAAAP) platform, which involves peripheral blood mononuclear cell (PBMC)-derived natural killer (NK)-like cells armed with proprietary antibodies. This specific candidate targets tumor cells expressing a proprietary, undisclosed antigen referred to as 'antigen B+'. Unlike traditional CAR-T or CAR-NK therapies, the GAAAP platform does not require genetic modification of the cells, facilitating an 'off-the-shelf' therapeutic model. The therapy is administered intravenously for the treatment of B+ tumors.

Other names: GAAAP antibody-armed NK-like cell (B+)

Beyond the preview

Go deeper on GAIA-121-125 (B+).

Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.

Clinical trials

Follow clinical development from study design and recruitment through results.

Trial phase
Status
Readouts

Indications & development

Explore development by indication, patient population, and geography.

Indications
Development status
Countries

Licensing & deals

Trace asset ownership, licensing agreements, and commercial partnerships.

Partners
Deal terms
Milestones

Patents & exclusivity

Explore the patent landscape and regulatory exclusivity around an asset.

Patents
Expiration dates
Exclusivity

Competitive landscape

Compare development programs by target, modality, and indication.

Competing assets
Targets
Development stage

Research & analysis

Connect source evidence and development news to your research questions.

Publications
News
Analysis

Bring the full picture into focus.

See how Gosset can support your research on GAIA-121-125 (B+).

Explore the full profile