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ganoderma lucidum + saffron extract
- Development stage
- Unknown
- Lead developer
- Peking University School and Hospital of Stomatology
- Modality
- Small Molecules
- Administration
- Topical
01
Overview
A botanical combination therapy consisting of extracts from *Ganoderma lucidum* (Reishi mushroom) and *Crocus sativus* (Saffron), developed by the Peking University Hospital of Stomatology. This formulation is designed to target oral inflammatory conditions such as gingivitis and periodontal disease. *Ganoderma lucidum* contains bioactive triterpenoids and polysaccharides that exhibit significant anti-inflammatory and immunomodulatory properties, while saffron extract provides potent antioxidant effects through compounds like crocin and crocetin. The combination works synergistically to reduce dental plaque accumulation and alleviate gingival inflammation by modulating the local immune response and inhibiting pro-inflammatory signaling pathways, specifically targeting cytokines such as TNF-α and IL-6.
- Brand names
- Lingzhi Saffron Mouthwash
- Other names
- Lingzhi SaffronGanoderma lucidum and Crocus sativus extract
02
Targets
TLR (Toll-like receptors)
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