Drug intelligence / Profile preview

Gatorade + polyethylene glycol 3350

Development stage
Unknown
Lead developer
Braintree
Modality
Drug Delivery Systems, Small Molecules
Administration
Oral
01

Overview

Gatorade + polyethylene glycol 3350 is a non-prescription bowel preparation regimen commonly used prior to colonoscopy or certain surgeries. It consists of mixing a specified amount of polyethylene glycol 3350 (PEG 3350), an osmotic laxative, with the sports drink Gatorade. PEG 3350 works by retaining water in the stool through osmotic action, leading to increased stool frequency and liquidity for effective colon cleansing. The addition of Gatorade provides electrolytes and flavoring, improving palatability and patient tolerance compared to traditional electrolyte-balanced PEG solutions. This combination is not FDA-approved for bowel prep but is widely used off-label due to its safety profile and patient satisfaction[1][2][5][6]. Studies show it is non-inferior in efficacy to standard prescription preparations when used as directed[1].

Brand names
MiraLAXGatorade
Other names
MiraLAX + GatoradePEG 3350 + Gatoradepolyethylene glycol 3350 + sports drink

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