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general anesthesia + caudal block with levobupivacaine
- Development stage
- Unknown
- Lead developer
- University of Novi Sad
- Modality
- Small Molecules
- Administration
- Intravenous, Oral, Caudal
01
Overview
A multimodal anesthetic and analgesic regimen developed by the University of Novi Sad for pediatric patients undergoing inguinal hernioplasty. The protocol combines a standardized general anesthesia (GA) induction—utilizing midazolam for premedication, propofol for induction, fentanyl for analgesia, and rocuronium for muscle relaxation—with a single-shot caudal block (CB) using 0.25% levobupivacaine. This combination is designed to optimize perioperative pain management by leveraging the synergistic effects of systemic anesthetics and regional blockade, thereby improving hemodynamic stability and reducing the overall consumption of intraoperative and postoperative analgesics.
- Other names
- general anesthesia-University of Novi Sad-postoperative painGA + Caudal BlockGeneral anesthesia with caudal block
02
Targets
NaV (Voltage-gated sodium channels)GABRR (GABA-A receptor subunit rho)
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