ginseng + branched-chain amino acids

A non-pharmaceutical **combination dietary supplement** composed of **ginseng** (commonly Panax ginseng) and **branched-chain amino acids** (BCAAs: leucine, isoleucine, and valine). This combination is primarily marketed and studied for its potential to improve exercise performance, reduce central fatigue, and enhance attention during strenuous activity. Mechanistically, BCAAs are believed to promote muscle protein synthesis and reduce muscle breakdown, likely through the mTOR pathway, while ginseng is attributed with adaptogenic properties and potential to enhance cognitive function, modulate fatigue, and support physical endurance. There is evidence from at least one placebo-controlled clinical trial suggesting the combination may improve attentional performance and subjective fatigue in the context of exercise[2][6].