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ginseng + radix bupleuri

Development stage
Preclinical
Modality
Small Molecules
Administration
Oral
01

Overview

This is a combination of two traditional herbal medicines widely used in East Asian medicine—Panax ginseng (Ginseng radix) and Bupleurum root (Bupleuri radix). Both herbs are known for their immunomodulatory, anti-inflammatory, hepatoprotective, and adaptogenic properties. In preclinical studies, the combination has been shown to increase the amplitude of spontaneous activity in lymphatic vessels and enhance lymph flow independently of endothelial cells. The active constituents include ginsenosides from Panax ginseng and saikosaponins from Bupleurum root. These compounds have demonstrated effects such as modulation of immune function, anti-inflammatory action via inhibition of pro-inflammatory cytokines and mediators, antiviral activity against enveloped viruses (for bupleurum), hepatoprotection through antioxidant mechanisms, and possible metabolic benefits. This combination is primarily used in traditional medicine formulas for supporting immune health, liver function, stress adaptation, and general vitality[1][2][3].

Other names
Panax ginseng + Bupleuri radixGinseng radix + Bupleuri radixGinseng root + Bupleurum root
02

Targets

PPARG (Peroxisome proliferator-activated receptor gamma)

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