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glucagon (Eli Lilly and Company)
- Development stage
- Approved
- Lead developer
- Eli Lilly
- Modality
- Recombinant Proteins and Enzymes
- Administration
- Intranasal, Intravenous, Subcutaneous
01
Overview
Glucagon (nasal) is a recombinant form of the human hormone glucagon formulated as a dry powder for intranasal administration. It is used as an emergency treatment for severe hypoglycemia in patients with diabetes aged 4 years and older. The drug works by stimulating hepatic glycogenolysis, causing the liver to release stored glucose into the bloodstream and rapidly increasing blood glucose levels. Nasal delivery allows for rapid absorption through the nasal mucosa without requiring inhalation or injection, making it suitable for use when intravenous or subcutaneous administration is not feasible. The primary developer and manufacturer of this formulation is Eli Lilly. The main indication is severe hypoglycemia in diabetes[1][2][3][4][5][6][8].
- Brand names
- Baqsimi
- Other names
- nasal glucagonglucagon nasal powderintranasal glucagon
02
Targets
GCGR (Glucagon receptor)
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