Drug intelligence / Profile preview

glucagon (porcine)

Development stage
Unknown
Modality
Peptides
Administration
Intramuscular, Intravenous, Subcutaneous
01

Overview

Porcine glucagon is a **29-amino-acid peptide hormone** preparation derived from or corresponding to the porcine form of glucagon, historically used as an **antihypoglycemic agent** and **gastrointestinal motility inhibitor**. It acts as an **agonist of the glucagon receptor**, primarily on hepatocytes, activating adenylate cyclase and increasing intracellular cAMP, which promotes **glycogenolysis** and **gluconeogenesis** and thereby raises blood glucose. Clinically, glucagon products have been used for the emergency treatment of severe hypoglycemia and as a diagnostic aid during radiologic examinations to transiently inhibit GI motility. For the exact entity requested here, the qualifier indicates the **porcine peptide form**, which is biologically very similar to human glucagon but should be treated as a distinct specified peptide source/form rather than collapsed into generic glucagon.

Other names
glucagon (porcine)porcine glucagon
02

Targets

GCGR (Glucagon receptor)

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