Drug intelligence / Profile preview

glucocorticoid + recombinant human thrombopoietin

Development stage
Unknown
Lead developer
3SBio
Modality
Recombinant Proteins and Enzymes, Small Molecules
Administration
Oral, Intravenous, Subcutaneous
01

Overview

A combination therapy consisting of glucocorticoids and recombinant human thrombopoietin (rhTPO). This combination is primarily used for treating immune thrombocytopenia (ITP) and has shown enhanced efficacy compared to glucocorticoids alone. The therapy works by promoting platelet production through rhTPO while modulating immune response through glucocorticoids. Clinical studies have demonstrated higher response rates, faster platelet count recovery, and improved T lymphocyte regulation with this combination.

Other names
rhTPO + glucocorticoids
02

Targets

GR (Glucocorticoid receptor)TPOR (Thrombopoietin receptor)

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