Clinical trials
Full profile accessFollow clinical development from study design and recruitment through results.
- Trial phase
- Status
- Readouts
Drug intelligence / Profile preview
glucocorticoid + tacrolimus
- Development stage
- Unknown
- Lead developer
- Astellas Pharma
- Modality
- Small Molecules
- Administration
- Oral, Intravenous
01
Overview
A combination immunosuppressive therapy consisting of a glucocorticoid and tacrolimus, primarily used to prevent organ rejection in transplant recipients. Tacrolimus is a calcineurin inhibitor that inhibits T-cell activation by preventing the dephosphorylation reactions required for lymphokine gene transcription. Glucocorticoids provide complementary immunosuppressive effects through different mechanisms. This combination is often used with other immunosuppressants like mycophenolate mofetil in transplant protocols.
- Other names
- tacrolimus plus corticosteroidstacrolimus + corticosteroidstacrolimus + prednisolonetacrolimus + prednisonetacrolimus + methylprednisolonetacrolimus + glucocorticoids
02
Targets
GR (Glucocorticoid receptor)FKBP1ACN (Calcineurin)
Beyond the preview
Go deeper on glucocorticoid + tacrolimus.
Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.
Indications & development
Full profile accessExplore development by indication, patient population, and geography.
- Indications
- Development status
- Countries
Licensing & deals
Full profile accessTrace asset ownership, licensing agreements, and commercial partnerships.
- Partners
- Deal terms
- Milestones
Patents & exclusivity
Full profile accessExplore the patent landscape and regulatory exclusivity around an asset.
- Patents
- Expiration dates
- Exclusivity
Competitive landscape
Full profile accessCompare development programs by target, modality, and indication.
- Competing assets
- Targets
- Development stage
Research & analysis
Full profile accessConnect source evidence and development news to your research questions.
- Publications
- News
- Analysis
Bring the full picture into focus.
See how Gosset can support your research on glucocorticoid + tacrolimus.