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glucosamine sulfate + ginkgo biloba
- Development stage
- Unknown
- Lead developer
- KGK Science
- Modality
- Metabolically Activated Prodrugs → Prodrugs/Conditional Activator Small Molecules → Small Molecules, Classical Binding Small Molecules → Small Molecules
- Administration
- Oral
01
Overview
Glucosamine sulfate + ginkgo biloba is a combination product consisting of the amino sugar glucosamine sulfate and a standardized extract from the leaves of the *Ginkgo biloba* tree. Primarily studied as a natural health product or dietary supplement, this combination is investigated for its therapeutic potential in managing osteoarthritis, particularly of the knee, and for its potential antifungal properties. Glucosamine sulfate serves as a biochemical precursor for glycosaminoglycans and proteoglycans, which are essential components of articular cartilage matrix. *Ginkgo biloba* extract contributes antioxidant, anti-inflammatory, and circulatory-enhancing effects, partially through the antagonism of platelet-activating factor (PAF) receptors. Clinical research, including trials organized by KGK Science Inc., has evaluated the efficacy of this combination in reducing joint pain as measured by the WOMAC index, suggesting it may offer superior clinical utility compared to glucosamine alone or in combination with chondroitin.
- Other names
- glucosamine sulphate + ginkgo biloba
02
Targets
NF-κBPTAFR (Platelet-activating factor receptor)
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