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glutamine + probiotics
- Development stage
- Unknown
- Lead developer
- Xi'an Hospital of Traditional Chinese Medicine
- Modality
- Synthetic Biology Platforms → Engineered Microbial Therapeutics → Microbiome Therapeutics, Fresh FMT → Fecal Microbiota Transplantation (FMT) → Microbiome Therapeutics, Small Molecules, Yeast Strains → Single Strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Bacterial Strains → Single Strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Defined Consortia → Multi-strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Frozen FMT → Fecal Microbiota Transplantation (FMT) → Microbiome Therapeutics, Genetically Modified Bacteria → Engineered Microbial Therapeutics → Microbiome Therapeutics, Microbial Metabolites → Microbiome-Derived Products → Microbiome Therapeutics, Microbial Proteins → Microbiome-Derived Products → Microbiome Therapeutics, Complex Communities → Multi-strain Products → Live Biotherapeutic Products → Microbiome Therapeutics
- Administration
- Oral
01
Overview
The combination of glutamine and probiotics is used as a standard control intervention in clinical research conducted by the Xi'an Hospital of Traditional Chinese Medicine, specifically for patients who have undergone colorectal polypectomy. Glutamine is an amino acid that serves as a primary metabolic fuel for enterocytes, supporting the maintenance and repair of the intestinal mucosal barrier post-surgery. Probiotics are live beneficial microorganisms administered to modulate and restore the balance and diversity of the gut microbiota. In the context of post-polypectomy management, this combination aims to improve gut health, regulate inflammatory markers such as IL-6 and TNF-α, and serve as a baseline comparator for evaluating the efficacy of Traditional Chinese Medicine (TCM) formulas like Modified Si-Ni-San on microbiota composition and the risk of polyp recurrence.
- Other names
- glutamine and probioticsglutamine compound and probiotics
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