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Glycerine + Magnesium Sulphate is a topical combination medication containing magnesium sulphate, an osmotic agent, and glycerine, a humectant. It is primarily used as an over-the-counter treatment for peripheral intravenous cannula (PIVC)-induced phlebitis, as well as for minor skin infections and inflammations such as boils, carbuncles, and infected nails. The mechanism of action involves magnesium sulphate creating an osmotic gradient that draws excess fluid and inflammatory exudate from the affected area, thereby reducing swelling, tension, and pain. Glycerine acts as a base that keeps the skin hydrated, prevents the formulation from drying out, and provides a mild antiseptic environment. This combination is a long-established preparation in clinical and home care settings, often formulated as a thick paste or ointment.
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