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**Glycerin + payayor** is a combination preparation, most likely for topical or rectal use. **Glycerin** (also known as glycerol) is an osmotic laxative and humectant, widely used in pharmaceuticals for its moisture-retaining properties and as a stool softener when used rectally. Its mechanism involves drawing water into the colon, softening stools, and promoting bowel movement. It can also act as a moisturizer and is commonly an excipient in topical and oral drugs[2][3][4][6][7][8]. **Payayor** (พญายอ, often referred to as "Phaya Yor," "Clinacanthus nutans") is a traditional Southeast Asian medicinal plant. In topical preparations, Payayor is used for its anti-inflammatory and skin-soothing properties, particularly in relief of rashes, minor burns, insect bites, and possibly as an antiviral agent. The mechanisms are not fully elucidated but are believed to involve anti-inflammatory and wound-healing pathways. This combination is likely formulated for use in skin conditions, hemorrhoids, or local irritation, leveraging glycerin's moisturizing/stool-softening properties and payayor's anti-inflammatory/skin-soothing actions.
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