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gouteng + xuanshen
- Development stage
- Unknown
- Lead developer
- Affiliated Hospital of Shandong University of Traditional Chinese Medicine
- Modality
- Metabolically Activated Prodrugs → Prodrugs/Conditional Activator Small Molecules → Small Molecules, Classical Binding Small Molecules → Small Molecules
- Administration
- Oral
01
Overview
Gouteng Xuanshen, also known as the Gouteng Xuanshen Prescription or GouTengXuanShen KeLi, is a Traditional Chinese Medicine (TCM) herbal formula primarily investigated for its antihypertensive properties. The formulation is composed of botanical extracts including *Uncaria rhynchophylla* (Gouteng), *Scrophularia ningpoensis* (Xuanshen), and *Raphani Semen* (Radish Seed). It is traditionally indicated for patients with hypertension or prehypertension presenting with Liver Yang Syndrome. The formula is typically administered as granules (KeLi) and has been the subject of retrospective cohort studies and clinical trials conducted by the Affiliated Hospital of Shandong University of Traditional Chinese Medicine to evaluate its efficacy in lowering blood pressure and managing high normal blood pressure levels.
- Other names
- Gouteng Xuanshen PrescriptionGouTengXuanShen KeLiGouteng Xuanshen Granules
02
Targets
LTCC (Voltage-gated calcium channel (L-type))
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