Drug intelligence / Profile preview

GPCR antagonist (Hope Medicine)

Development stage
Preclinical
Lead developer
HopeMed
Modality
Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules
01

Overview

GPCR antagonist (Program 1) is an investigational drug candidate being developed by Hope Medicine for the treatment of myocardial infarction. The drug acts as an antagonist of a G protein-coupled receptor (GPCR), a large family of cell surface receptors involved in various physiological and pathological processes, including cardiovascular signaling. By targeting a specific GPCR, the program aims to modulate pathways that contribute to cardiac injury or adverse remodeling following an ischemic event such as a heart attack. Currently in the early stages of development (exploratory or lead optimization), this program represents part of Hope Medicine's focus on leveraging GPCR biology to address unmet needs in cardiovascular and metabolic diseases.

Other names
GPCR antagonist (Program 1)

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