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grape seed extract + nicomethanol fluorhydrate

Development stage: Preclinical
Lead developer: Pierre Fabre
Modality: Small Molecules
Administration: Topical

Overview

A dental formulation combining grape seed extract with nicomethanol hydrofluoride (Fluorinol®), designed to enhance fluoride uptake by dental enamel. The grape seed extract contains polyphenols that work synergistically with the fluoride component to prevent dental biofilm formation and protect against tooth decay. Nicomethanol hydrofluoride helps the enamel take up five times more fluoride compared to standard mineral fluorides, promoting remineralization and making enamel more resistant to acid attacks.

Brand names: Elgydium
Other names: Grape seed extract + Fluorinol

Targets

Dental bacterial biofilm

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