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This is a combination treatment regimen for tinea capitis (scalp ringworm) that includes oral griseofulvin and topical antifungal shampoos. The regimen consists of oral griseofulvin for systemic treatment, combined with one of several antifungal shampoos (selenium sulfide, ketoconazole, or ciclopirox) or baby shampoo as a control. This combination approach aims to eradicate the fungal infection more quickly than oral therapy alone. Griseofulvin works by inhibiting fungal cell division, while the topical antifungal shampoos help reduce fungal spores on the scalp surface. This combination has been studied in clinical trials to determine which antifungal shampoo most effectively reduces time to cure and prevents recurrence when used alongside oral griseofulvin.
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