Drug intelligence / Profile preview

guaifenesin + pseudoephedrine hydrochloride

Development stage
Approved
Modality
Small Molecules
Administration
Oral
01

Overview

Guaifenesin + pseudoephedrine hydrochloride is an oral combination drug used to relieve symptoms associated with upper respiratory tract conditions, such as the common cold, allergies (hay fever), and other breathing illnesses. Guaifenesin acts as an expectorant by thinning and loosening mucus in the airways, making it easier to clear congestion. Pseudoephedrine is a sympathomimetic decongestant that works by constricting blood vessels in the nasal passages, thereby reducing swelling and congestion. This combination does not treat infections but provides symptomatic relief from cough with mucus, runny or stuffy nose, sneezing, sinus pain, watery eyes, and chest congestion. It is available over-the-counter in various dosage forms including tablets (regular and extended-release), capsules, and liquids. The product is marketed under numerous brand names worldwide.

Brand names
Mucinex DAmbifed-GEntex TMaxifedMucinex D Max StrengthAldex GSAltex-PSEAmbiAmbifedAmi-Tex PSEAquatab DColdmist JRColdmist LACongestacD Feda IIDecongest IIDeconsal IIDeconsal LADefen LADesal IIDrituss GPDurasal IIDuratuss
Other names
guaifenesin and pseudoephedrinepseudoephedrine-guaifenesinguaifenesin-pseudoephedrine
02

Targets

ADRB2 (β2)ADRA1A (α1A)ADRA2A (α2A)ADRB1 (β1)

Beyond the preview

Go deeper on guaifenesin + pseudoephedrine hydrochloride.

Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.

Clinical trials

Full profile access

Follow clinical development from study design and recruitment through results.

  • Trial phase
  • Status
  • Readouts

Indications & development

Full profile access

Explore development by indication, patient population, and geography.

  • Indications
  • Development status
  • Countries

Licensing & deals

Full profile access

Trace asset ownership, licensing agreements, and commercial partnerships.

  • Partners
  • Deal terms
  • Milestones

Patents & exclusivity

Full profile access

Explore the patent landscape and regulatory exclusivity around an asset.

  • Patents
  • Expiration dates
  • Exclusivity

Competitive landscape

Full profile access

Compare development programs by target, modality, and indication.

  • Competing assets
  • Targets
  • Development stage

Research & analysis

Full profile access

Connect source evidence and development news to your research questions.

  • Publications
  • News
  • Analysis

Bring the full picture into focus.

See how Gosset can support your research on guaifenesin + pseudoephedrine hydrochloride.

Explore the full profile

Gosset Free

Get started with Gosset.

Enter your work email and we’ll be in touch with next steps.

Work email preferred.

Book a call