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guanosine-5'-triphosphate

Development stage: Unknown
Modality: Small Molecules

Overview

Guanosine-5'-triphosphate (GTP) is a purine nucleoside triphosphate composed of the nucleobase guanine attached to a ribose sugar, which is further linked to three phosphate groups at the 5' position. It serves as an essential building block for RNA synthesis during transcription and acts as an energy source or activator in various metabolic reactions, similar to ATP but with more specific roles. GTP is crucial in protein synthesis, gluconeogenesis, and especially signal transduction via G-proteins in second-messenger systems where it is hydrolyzed by GTPases to GDP. It also functions as a phosphoryl donor in protein synthesis and cell signaling pathways[1][2][3][4][8].

Other names: guanosine triphosphateguanosine 5'-triphosphateH4GTPH-4GTPH 4GTP

Targets

GNASRNAP (Bacterial dna-dependent RNA polymerase)

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