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guiding phlegm decoction + lingjiao gouteng decoction
- Development stage
- Preclinical
- Lead developer
- Shaoxing Hospital of Traditional Chinese Medicine
- Administration
- Oral
01
Overview
Guiding Phlegm Decoction + Lingjiao Gouteng Decoction is a combination of two traditional Chinese medicine (TCM) formulas: Guiding Phlegm Decoction (Dao Tan Tang) and Lingjiao Gouteng Decoction (Ling Jiao Gou Teng Tang). This combination is being evaluated in clinical research, specifically as a comparator treatment for Parkinson's disease and associated constipation. Guiding Phlegm Decoction is traditionally used to resolve phlegm and regulate Qi, while Lingjiao Gouteng Decoction is used to clear heat, extinguish internal wind, and soothe the liver. The combination is intended to address the complex TCM patterns of phlegm-heat and internal wind-stirring often observed in patients with chronic neurological disorders.
- Other names
- Dao Tan Tang + Ling Jiao Gou Teng TangDaotan Decoction + Lingjiao Gouteng Decoction
02
Targets
Arachidonate 15-lipoxygenase/phosphatidylethanolamine-binding protein 1 complexFTH1 (Ferritin heavy chain 1)Glutathione peroxidase 4/E3 ubiquitin-protein ligase NEDD4 complex
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