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Gusongbao + rosa roxburghii
- Development stage
- Preclinical
- Lead developer
- Shenzhen University
- Modality
- Metabolically Activated Prodrugs → Prodrugs/Conditional Activator Small Molecules → Small Molecules, Classical Binding Small Molecules → Small Molecules
- Administration
- Oral
01
Overview
Gusongbao + rosa roxburghii is a combination product consisting of "Gusongbao" (骨松宝), a traditional Chinese medicine formulation, and "rosa roxburghii" (刺梨), also known as chestnut rose. This combination is being studied for its potential therapeutic effects, particularly in the treatment of endemic fluorosis (地方性氟中毒). Gusongbao itself is available as capsules or granules and is produced by Guizhou Fuhua Pharmaceutical. Rosa roxburghii is rich in vitamin C and polyphenols and has been used in functional foods and supplements for its antioxidant properties. The mechanism of action for this combination likely involves bone metabolism modulation from Gusongbao components alongside antioxidative and anti-inflammatory effects from rosa roxburghii. Research into this specific combination focuses on synergistic benefits for bone health and detoxification related to fluoride exposure[1][3][8].
- Brand names
- 骨松宝 + 刺梨
- Other names
- Gusongbao + rosa roxburghii骨松宝联合刺梨骨松宝联合刺梨汁
02
Targets
Sucrase-IsomaltaseIL-6 (Interleukin 6)TNFA (Tumor necrosis factor alpha (soluble))
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