Drug intelligence / Profile preview

HAIC + cadonilimab + bevacizumab

Development stage
Unknown
Lead developer
Akeso
Administration
Intra-arterial, Intravenous
01

Overview

This entry refers to a potential drug combination involving Hepatic Arterial Infusion Chemotherapy (HAIC), cadonilimab, and bevacizumab. Based on the provided search results, specific information about **HAIC** in this exact combination is not available. The search results focus on the combination of **cadonilimab** (AK104), a bispecific antibody targeting PD-1 and CTLA-4, and **bevacizumab** (Avastin), a monoclonal antibody targeting VEGF. This combination, often with chemotherapy, has shown promising results in clinical trials for recurrent and/or metastatic cervical cancer.

02

Targets

VEGFA (Vascular endothelial growth factor A)PDCD1 (Programmed cell death protein 1 receptor)CTLA-4 (Cytotoxic t-lymphocyte–associated protein 4)

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