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He Ji Gong Pain & Fever Relief Powder
- Development stage
- Unknown
- Lead developer
- Ho Chai Kung Medical Factory
- Modality
- Small Molecules
- Administration
- Oral
01
Overview
He Ji Gong Pain & Fever Relief Powder (何濟公止痛退熱散) is a traditional over-the-counter (OTC) analgesic and antipyretic medication developed by the Hong Kong-based company He Ji Gong (also known as Ho Chai Kung). The product is formulated as a combination of three active pharmaceutical ingredients: aspirin (acetylsalicylic acid), paracetamol (acetaminophen), and caffeine. It is widely used in Hong Kong and Southeast Asia for the rapid relief of symptoms associated with the common cold and influenza, including fever, headache, and muscular aches. Aspirin and paracetamol work synergistically to reduce pain and fever by inhibiting cyclooxygenase (COX) enzymes, thereby decreasing the synthesis of pro-inflammatory prostaglandins. Caffeine acts as an analgesic adjuvant, enhancing the efficacy of the pain-relieving components and helping to alleviate fatigue. The medication is typically administered orally as a powder, often packaged in individual sachets.
- Brand names
- He Ji Gong Pain & Fever Relief PowderHo Chai Kung Pain & Fever Relief Powder何濟公止痛退熱散
- Other names
- Ho Chai Kung Tze Thong Tui Yuet Shan
02
Targets
ADORA2A (Adenosine A₂A Receptor)PTGS2 (Prostaglandin-Endoperoxide Synthase 2)PGHS-1 (Prostaglandin G/H Synthase 1)ADORA1 (Adenosine receptor A1 subtype)
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