Drug intelligence / Profile preview

heparin sodium + allantoin

Development stage
Unknown
Lead developer
Merz Pharma
Modality
Small Molecules
Administration
Topical
01

Overview

Heparin sodium + allantoin is a topical combination therapy primarily utilized in dermatology for the treatment of scars and inflammatory skin conditions. Heparin sodium, a biological glycosaminoglycan, exerts anti-inflammatory, anti-proliferative, and anti-edematous effects when applied topically; it also promotes the hydration of collagen tissue and improves local microcirculation. Allantoin acts as a skin-conditioning agent that stimulates epithelialization, promotes wound healing, and possesses keratolytic and soothing properties. While traditionally indicated for hypertrophic and keloidal scars, recent clinical research, including studies by The Second Affiliated Hospital of Xi'an Jiaotong University, has explored its efficacy in treating rosacea by targeting inflammatory erythema and improving skin barrier function. In many regions, this combination is marketed as a 'compound' gel that may also include onion extract (Ext. Cepae).

Brand names
Contractubex
Other names
heparin sodium/allantoincompound heparin sodium and allantoin gel复方肝素钠尿囊素凝胶
02

Targets

F10 (Factor Xa)ATIII (Antithrombin III)F2 (Thrombin)

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