heparin sodium + allantoin + onion extract

Heparin sodium + allantoin + onion extract gel is a topical combination therapy widely used for the management and prevention of hypertrophic scars, keloids, and other types of pathological scarring resulting from surgery, burns, or trauma. The formulation typically contains three active ingredients: **heparin sodium**, which exerts anti-inflammatory and anti-proliferative effects by inhibiting fibroblast growth and promoting tissue hydration; **allantoin**, which facilitates wound healing, provides keratolytic effects to soften the scar tissue, and increases water-binding capacity; and **onion extract** (Extractum Cepae), which contributes additional anti-inflammatory properties and inhibits excessive collagen synthesis. Together, these components work synergistically to flatten scars, reduce redness, and alleviate symptoms such as itching and tension. It is often used as a standard-of-care topical treatment in clinical settings and has been evaluated in combination with other modalities, such as 5-fluorouracil and microneedle-assisted delivery systems.

Brand names

ContractubexMedermaKelofibrase

Other names

compound heparin sodium allantoin gelheparin sodium allantoin gelheparin sodium/allantoin/extractum cepae gel