heparinoid + escin + diethylamine salicylate

This is a **topical combination drug** gel containing **heparinoid**, **escin**, and **diethylamine salicylate**. It is formulated for cutaneous application in the treatment of **sports-related and blunt impact injuries** (strains, sprains, contusions), as well as musculoskeletal pain and venous insufficiency. - **Heparinoids** possess anticoagulant and anti-inflammatory properties, improving local blood flow and preventing clot formation. - **Escin** (from horse chestnut seed extract) exerts anti-inflammatory, anti-edematous, and venotonic effects, mainly by stabilizing endothelial barriers and reducing microvascular permeability. - **Diethylamine salicylate** is a topical NSAID with analgesic, anti-inflammatory, and counterirritant actions, reducing musculoskeletal pain and inflammation. The gel demonstrates superior efficacy in reducing pain, tenderness, and swelling versus placebo and some single-ingredient comparators, with a rapid onset of symptom relief and a good safety profile[2][4][7].