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hepatitis a vaccine (inactivated, HM175 strain)
- Development stage
- Approved
- Lead developer
- GSK
- Modality
- Vaccines & Immunotherapeutics
- Administration
- Intramuscular
01
Overview
Hepatitis a vaccine (inactivated, HM175 strain) is an **inactivated viral vaccine** developed by **GSK** and marketed as **Havrix** for active immunization against hepatitis A virus infection. The vaccine contains **formaldehyde-inactivated hepatitis A virus strain HM175** produced in **MRC-5 human diploid cells**, purified and adsorbed to an aluminum-based adjuvant, and is administered to induce protective anti-HAV antibody responses. It is indicated for prevention of hepatitis A disease in individuals **12 months of age and older**, with marketed pediatric and adult dose strengths, and clinical studies showed high seroconversion after the first dose and protective efficacy of about 95%.
- Brand names
- Havrix
- Other names
- hepatitis a vaccine (inactivated, HM175 strain)inactivated hepatitis a virus vaccinehepatitis a vaccine inactivated
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