Drug intelligence / Profile preview

HGP0608 + HGP0816

Development stage
Unknown
Lead developer
Hanmi Pharmaceutical
Modality
Small Molecules
Administration
Oral
01

Overview

HGP0608 + HGP0816 is a pharmaceutical combination evaluated in clinical trials for the treatment of hypertension and dyslipidemia, typically administered together with HGP0904. The combination includes HGP0608 (losartan, an angiotensin II receptor blocker/antihypertensive) and HGP0816 (rosuvastatin, an HMG-CoA reductase inhibitor/statin for cholesterol management). The main mechanism is the dual control of blood pressure and cholesterol, targeting cardiovascular risk reduction. Development and trials have been conducted primarily by Hanmi Pharmaceutical. The combination is not a fixed-dose product but rather the co-administration of these agents, sometimes alongside HGP0904 (amlodipine)[2][3].

02

Targets

HMGCR (3-hydroxy-3-methylglutaryl-coenzyme A reductase)AGTR1 (Angiotensin II Type-1 receptor)

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