Drug intelligence / Profile preview

honey + Nigella sativa

Development stage
Unknown
Lead developer
Sohaib Ashraf
Modality
Small Molecules
Administration
Oral
01

Overview

A combination of raw natural honey and Nigella sativa (black cumin) seeds investigated for the treatment of COVID-19. This natural product intervention was evaluated in the HNS-COVID-PK trial, a multicenter, randomized, placebo-controlled study conducted in Pakistan by Dr. Sohaib Ashraf and colleagues at the Shaikh Zayed Post-Graduate Medical Institute. The regimen consists of 1 g/kg/day of honey and 80 mg/kg/day of Nigella sativa seeds administered orally for up to 13 days. The combination is hypothesized to provide synergistic benefits through antiviral, anti-inflammatory, and immunomodulatory mechanisms. Clinical findings published in 2023 indicated that the intervention significantly improved symptom recovery, viral clearance, and 30-day mortality in patients with moderate to severe COVID-19.

Other names
Honey and Nigella sativaHNS-COVID-PK intervention
02

Targets

PTGS2 (Prostaglandin-Endoperoxide Synthase 2)TP53 (Cellular Tumor Antigen p53 R175H)Mpro (3C-like proteinase of SARS-CoV-2)GCK (Glucokinase)

Beyond the preview

Go deeper on honey + Nigella sativa.

Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.

Clinical trials

Full profile access

Follow clinical development from study design and recruitment through results.

  • Trial phase
  • Status
  • Readouts

Indications & development

Full profile access

Explore development by indication, patient population, and geography.

  • Indications
  • Development status
  • Countries

Licensing & deals

Full profile access

Trace asset ownership, licensing agreements, and commercial partnerships.

  • Partners
  • Deal terms
  • Milestones

Patents & exclusivity

Full profile access

Explore the patent landscape and regulatory exclusivity around an asset.

  • Patents
  • Expiration dates
  • Exclusivity

Competitive landscape

Full profile access

Compare development programs by target, modality, and indication.

  • Competing assets
  • Targets
  • Development stage

Research & analysis

Full profile access

Connect source evidence and development news to your research questions.

  • Publications
  • News
  • Analysis

Bring the full picture into focus.

See how Gosset can support your research on honey + Nigella sativa.

Explore the full profile

Gosset Free

Get started with Gosset.

Enter your work email and we’ll be in touch with next steps.

Work email preferred.

Book a call