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Hope Medicine kinase inhibitor (cancer cachexia)

Development stage
Preclinical
Lead developer
HopeMed
Modality
Bivalent/Multivalent Binders → Multivalent & Scaffold-Based Small Molecules → Small Molecules, Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules, Reversible Covalent Inhibitors → Covalent Small Molecules → Small Molecules, Allosteric Modulators → Classical Binding Small Molecules → Small Molecules, Irreversible Covalent Inhibitors → Covalent Small Molecules → Small Molecules, Fragment-Derived Small Molecules → Multivalent & Scaffold-Based Small Molecules → Small Molecules
01

Overview

Hope Medicine is developing an undisclosed kinase inhibitor, currently identified as Kinase Inhibitor (Program 1), for the treatment of cancer cachexia. Cancer cachexia is a complex metabolic syndrome characterized by the progressive loss of skeletal muscle mass and body weight in cancer patients, which significantly impacts quality of life and clinical outcomes. This program is part of Hope Medicine's early-stage pipeline, focusing on modulating kinase-mediated signaling pathways that contribute to muscle wasting or systemic inflammation associated with malignancy. While the specific molecular target and developmental stage have not been publicly disclosed, the program represents a targeted approach to addressing the unmet medical need in oncology-related metabolic dysfunction.

Other names
Kinase Inhibitor (Program 1)

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