Drug intelligence / Profile preview

house dust mite + alternaria extract

Development stage
Unknown
Lead developer
ALK Abelló
Modality
Allergy Immunotherapy → Therapeutic Vaccines → Vaccines & Immunotherapeutics
Administration
Sublingual, Subcutaneous
01

Overview

A combination allergen extract containing both house dust mite and Alternaria (a common mold) extracts, used in allergen immunotherapy for the treatment of allergic diseases such as allergic rhinitis or asthma. This therapy works by gradually exposing the immune system to small, controlled amounts of these allergens to induce tolerance and reduce symptoms over time. The mechanism involves modulation of the immune response, shifting from an IgE-mediated hypersensitivity reaction toward a more regulated or tolerant state. This combination is typically administered as part of allergy shots (subcutaneous immunotherapy) or custom-mixed sublingual drops/tablets prepared by allergists for patients with confirmed sensitivities to both allergens[3][6][8]. House dust mite and Alternaria are among the most common indoor allergens implicated in perennial allergic rhinitis and asthma.

02

Targets

IgE (Immunoglobulin E)

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