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HP-1050 is an investigational **transdermal hormonal contraceptive system** developed by Noven Pharmaceuticals. It was evaluated in a randomized, evaluator-blinded Phase 1 study in healthy adult females to assess cumulative skin irritation and sensitization relative to the norelgestromin and ethinyl estradiol contraceptive patch Xulane. Public trial materials do not disclose HP-1050's precise active-ingredient composition, dose, or pharmacologic target; therefore, it should not be equated with Xulane or assigned Xulane's ingredients solely on the basis of the comparator study. ([clinicaltrials.gov](https://clinicaltrials.gov/study/NCT04624867))
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