human pancreatic islets (Emory University)

Human pancreatic islet transplantation is a cell-based therapy developed and studied by Emory University for the treatment of type 1 diabetes mellitus. The therapy involves the isolation of insulin-producing islets from cadaveric donor pancreases, which are then infused into the patient's portal vein. This procedure aims to restore glycemic control and achieve insulin independence, particularly in patients suffering from life-threatening hypoglycemia or hypoglycemic unawareness. The Emory University protocol follows the steroid-free Edmonton Protocol, utilizing an immunosuppressive regimen typically consisting of sirolimus, tacrolimus, and daclizumab to prevent graft rejection.

Other names

human isletspurified human pancreatic isletsislet transplantationallogeneic pancreatic islets