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human umbilical cord mesenchymal stem cells (Affiliated Hospital to Academy of Military Medical Sciences)
- Development stage
- Unknown
- Lead developer
- Academy of Military Medical Sciences
- Modality
- Stem Cell Therapies → Cell Therapies
- Administration
- Intravenous
01
Overview
Human umbilical cord mesenchymal stem cells (hUC-MSCs) are multipotent stromal cells harvested from the Wharton's jelly of the umbilical cord. This specific cell therapy product is being developed and evaluated by the Affiliated Hospital to Academy of Military Medical Sciences for the treatment of ischemic stroke. The therapy is administered via intravenous infusion, typically in repeated doses. hUC-MSCs are hypothesized to function through paracrine mechanisms, secreting a variety of neurotrophic factors, anti-inflammatory cytokines, and angiogenic factors that migrate to the site of brain injury. These factors help to mitigate neuroinflammation, provide neuroprotection to the penumbra, and stimulate endogenous neural stem cell proliferation and tissue repair, thereby improving functional recovery in patients following a recent stroke.
- Other names
- Umbilical cord derived mesenchymal stem cellshUC-MSC for Ischemic Stroke
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