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human umbilical cord mesenchymal stem cells (Second Affiliated Hospital of Zhejiang University School of Medicine)
- Development stage
- Unknown
- Lead developer
- Second Affiliated Hospital of Zhejiang University School of Medicine
- Modality
- Stem Cell Therapies → Cell Therapies
- Administration
- Intracavitary
01
Overview
Human umbilical cord mesenchymal stem cells (hUMSCs) are multipotent stromal cells derived from umbilical cord tissue, specifically Wharton's jelly. In a clinical program led by the Second Affiliated Hospital, School of Medicine, Zhejiang University, these cells are being investigated for the treatment of acute basal ganglia hemorrhage. The therapeutic protocol involves a single intracavitary injection of hUMSCs into the hematoma cavity approximately 24 hours after stereotactic aspiration surgery. The cells are intended to mitigate secondary brain injury by modulating the local inflammatory response and promoting neural regeneration through the release of neurotrophic factors. This Phase 2 trial aims to evaluate the safety and efficacy of this cell-based intervention in improving neurological recovery and long-term prognosis for patients with spontaneous cerebral hemorrhage.
- Other names
- hUMSCshuman umbilical cord-derived mesenchymal stem cellsUC-MSCs
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