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Hyalograft C (Fidia Advanced Biopolymers)
- Development stage
- Discontinued
- Lead developer
- Anika Therapeutics
- Modality
- Implantable Hydrogels → Hydrogel Systems → Drug Delivery Systems, Implantable Devices → Device-based Delivery → Drug Delivery Systems, Cell Therapies, Injectable Hydrogels → Hydrogel Systems → Drug Delivery Systems
- Administration
- Implant
01
Overview
**Hyalograft C** is a patient-specific, matrix-associated autologous chondrocyte transplantation product for surgical cartilage repair. It contains autologous chondrocytes harvested from the patient, expanded ex vivo, and seeded onto a three-dimensional HYAFF-11 scaffold composed of esterified hyaluronic acid; the implanted construct is intended to fill focal cartilage defects and support regeneration of cartilage-like tissue. It was developed for symptomatic traumatic full-thickness cartilage defects of the medial or lateral femoral condyle or trochlea of the knee in adults. The product is a combined advanced therapy medicinal product because the cell therapy incorporates a scaffold medical device. ([ema.europa.eu](https://www.ema.europa.eu/en/medicines/human/EPAR/hyalograft-c-autograft))
- Brand names
- Hyalograft C
- Other names
- Hyalograft C autograftHyalograft-C
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