hyaluronic acid + clodronate disodium

Hyaluronic acid + clodronate disodium is a combination medical device with an ancillary drug substance being developed by Abiogen Pharma for the treatment of pain associated with joint disorders, specifically knee osteoarthritis. The product is formulated as single-dose vials for intra-articular injection. It combines hyaluronic acid, which serves as a viscosupplement and lubricant to restore joint mechanics and provide shock absorption, with clodronate disodium, a non-nitrogenous bisphosphonate that exerts anti-inflammatory and potential chondroprotective effects. By addressing both the mechanical degradation of the synovial fluid and the inflammatory processes within the joint, this combination therapy aims to provide superior pain relief and functional improvement compared to hyaluronic acid alone.

Other names

HA + Clodronate single-dose vialsHyaluronic acid with clodronate disodium