hydrocortisone + vitamin D

Hydrocortisone + vitamin D is a combination of two agents commonly used in clinical practice, though not typically formulated together as a single pharmaceutical product. Hydrocortisone is a synthetic glucocorticoid corticosteroid with potent anti-inflammatory and immunosuppressive properties, acting primarily through binding to the glucocorticoid receptor and modulating gene expression to suppress inflammation and immune responses[4]. Vitamin D refers to either cholecalciferol (vitamin D3) or ergocalciferol (vitamin D2), both of which are essential for calcium homeostasis, bone health, and modulation of immune function. When used together—often in patients requiring long-term corticosteroid therapy—vitamin D supplementation helps counteract the risk of osteoporosis associated with chronic hydrocortisone use by supporting bone mineralization[3][5]. There is no unique brand or code name for this combination; it is generally prescribed as separate agents.