Drug intelligence / Profile preview

hydrocortisone hemisuccinate + terbutaline

Development stage
Preclinical
Modality
Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules
Administration
Inhalation, Intramuscular, Intravenous, Subcutaneous
01

Overview

This is a combination drug consisting of hydrocortisone hemisuccinate, a synthetic glucocorticoid corticosteroid, and terbutaline, a selective beta-2 adrenergic receptor agonist. Hydrocortisone hemisuccinate acts as an anti-inflammatory and immunosuppressive agent by binding to the glucocorticoid receptor, reducing inflammation and immune responses[4][8]. Terbutaline stimulates beta-2 adrenergic receptors in bronchial smooth muscle, leading to bronchodilation and relief of bronchospasm[10]. The combination is used primarily for acute management of respiratory conditions such as asthma exacerbations or chronic obstructive pulmonary disease (COPD) where both rapid anti-inflammatory action and bronchodilation are required. Clinical studies suggest that the combined use can improve lung function parameters (such as FEV1, FVC) more effectively than either agent alone in acute exacerbations of COPD[7].

02

Targets

ADRB2 (β2)GR (Glucocorticoid receptor)

Beyond the preview

Go deeper on hydrocortisone hemisuccinate + terbutaline.

Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.

Clinical trials

Full profile access

Follow clinical development from study design and recruitment through results.

  • Trial phase
  • Status
  • Readouts

Indications & development

Full profile access

Explore development by indication, patient population, and geography.

  • Indications
  • Development status
  • Countries

Licensing & deals

Full profile access

Trace asset ownership, licensing agreements, and commercial partnerships.

  • Partners
  • Deal terms
  • Milestones

Patents & exclusivity

Full profile access

Explore the patent landscape and regulatory exclusivity around an asset.

  • Patents
  • Expiration dates
  • Exclusivity

Competitive landscape

Full profile access

Compare development programs by target, modality, and indication.

  • Competing assets
  • Targets
  • Development stage

Research & analysis

Full profile access

Connect source evidence and development news to your research questions.

  • Publications
  • News
  • Analysis

Bring the full picture into focus.

See how Gosset can support your research on hydrocortisone hemisuccinate + terbutaline.

Explore the full profile

Gosset Free

Get started with Gosset.

Enter your work email and we’ll be in touch with next steps.

Work email preferred.

Book a call