Drug intelligence / Profile preview

hydroquinone + mometasone + tretinoin

Development stage
Unknown
Lead developer
Microwin Labs
Modality
Small Molecules
Administration
Topical
01

Overview

Pearl Shine Cream is a topical dermatological medication developed by Microwin Labs, primarily indicated for the treatment of moderate-to-severe melasma and facial hyperpigmentation. It is a triple-combination therapy typically formulated with hydroquinone, tretinoin, and mometasone furoate. Hydroquinone acts as a skin-bleaching agent by inhibiting the enzyme tyrosinase, thereby reducing melanin synthesis. Tretinoin, a retinoid, promotes epithelial cell turnover and enhances the penetration of hydroquinone. Mometasone furoate, a medium-potency corticosteroid, is included to mitigate the inflammatory response and irritation often associated with the other two active components. This combination is widely marketed in the Indian pharmaceutical sector as a generic treatment for dark skin patches caused by sun exposure, hormonal changes, or aging.

Brand names
Pearl Shine Cream
Other names
Pearl Shine
02

Targets

RARA (Retinoic acid receptor alpha)TYR (Tyrosinase)GR (Glucocorticoid receptor)

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