hydroxychloroquine + prednisone

Hydroxychloroquine + prednisone is a combination therapy involving two distinct pharmaceutical agents commonly used in the management of autoimmune and inflammatory diseases, such as rheumatoid arthritis and systemic lupus erythematosus. Hydroxychloroquine is an antimalarial agent that also acts as a disease-modifying anti-rheumatic drug (DMARD), primarily by antagonizing toll-like receptors 7 and 9, thereby modulating immune system activity and reducing inflammation. Prednisone is a synthetic glucocorticoid corticosteroid that exerts potent anti-inflammatory and immunosuppressive effects by binding to the glucocorticoid receptor, influencing gene expression to suppress pro-inflammatory cytokines. This combination may be prescribed together to achieve better control of disease activity while potentially allowing for lower doses of corticosteroids, thus minimizing steroid-related side effects[2][3][7]. Both drugs are small molecules taken orally.

Brand names

Plaquenil

Other names

Hydroxychloroquine + low-dose prednisoneHydroxychloroquine and low-dose prednisoneHCQ + prednisone