hydroxyethyl starch + albumin

Hydroxyethyl starch (HES) and albumin are two distinct colloid solutions used for plasma volume expansion in clinical settings. They are often compared or used as alternatives to each other, rather than being a single combination product. Hydroxyethyl starch is a synthetic colloid used for preventing shock following severe blood loss caused by trauma, surgery, or other issues. It's available in various formulations, with 6% HES 130/0.4 being a common version. HES may reduce capillary leakage and maintains blood volume for at least 6 hours after administration[3][8]. Albumin (typically 5% concentration) is a natural plasma protein that serves as an alternative colloid for volume replacement. It interacts with the endothelial glycocalyx, which appears to provide protective effects on the vascular barrier[1]. Both solutions are used in perioperative fluid management, hypovolemia treatment, and other clinical scenarios requiring plasma volume expansion[1][2][6].

Other names

HES + albumin