hydroxyproline + leucine

Hydroxyproline + leucine is a combination of two amino acids primarily investigated for its potential synergistic effects on collagen synthesis, skin health, and muscle protein metabolism. Hydroxyproline is a major constituent of collagen, while leucine is an essential branched-chain amino acid (BCAA) that acts as a potent activator of the mechanistic target of rapamycin complex 1 (mTORC1) signaling pathway, which regulates protein synthesis. This combination is often found in dietary supplements and medical foods aimed at improving skin elasticity, supporting joint health, or mitigating age-related muscle loss (sarcopenia). Clinical research has explored its efficacy in enhancing muscle mass and skin rejuvenation, suggesting that the two components work together to stimulate tissue repair and anabolic processes.

Other names

L-hydroxyproline + L-leucine