ibuprofen + methocarbamol

Ibuprofen + methocarbamol is an oral fixed-dose combination of two active pharmaceutical ingredients: ibuprofen and methocarbamol. **Ibuprofen** is a nonsteroidal anti-inflammatory drug (NSAID) that blocks cyclooxygenase enzymes (COX-1 and COX-2), reducing prostaglandin synthesis and thereby lowering pain, fever, and inflammation. **Methocarbamol** is a centrally acting muscle relaxant that acts mainly at the level of the central nervous system (spinal cord and brain), reducing muscle hyperactivity and spasms through CNS depression, though its precise mechanism remains incompletely defined. This combination provides symptomatic treatment of pain associated with muscle spasm, including back pain, muscle strains and sprains, and tense neck muscles. The combination is designed for short-term relief, aiming to combine analgesic, anti-inflammatory, and muscle relaxant effects[1][3][5][9].

Brand names

Robax PlatinumRobi-MIbugesic M

Other names

ibuprofen + methocarbamol