imidacloprid + pyriproxyfen

Imidacloprid + pyriproxyfen is a combination topical antiparasitic drug used in veterinary medicine, primarily for dogs and cats, to treat and prevent flea infestations and, in some cases, lice. **Imidacloprid** is a neonicotinoid insecticide that acts as a nicotinic acetylcholine receptor agonist, causing paralysis and death in adult fleas and lice. **Pyriproxyfen** is an insect growth regulator (IGR) that mimics juvenile insect hormones, inhibiting the development and maturation of flea eggs and larvae, thereby breaking the flea life cycle. The product is usually formulated as a spot-on solution applied to the animal’s skin monthly. It is distinct from other combinations that include permethrin, which are only for dogs[2][9][11][13].

Brand names

Advantage IIAdvantage PlusProvecta II